• Period: Jan 2025 ~ Present

• Employment

Aug 2023 ~ Sep 2024, Researcher, IMBiologics

Apr 2021 ~ Feb 2023, Researcher, APROGEN

• Education

Mar 2016 ~ Feb 2021, B.S., Microbiology, Dankook University

• Project

(1) Deep Learning Algorithm-Based Design of Peptide inhibitor

(2) Development of an LC-MS/MS-Based Analytical Method for Cultured Meat

• Summary

Focusing on protein system research, I am working on an AI-based peptide inhibitor design project and an analytical method development project using LC-MS/MS technology. First, I use advanced AI-based protein design platforms such as RFdiffusion and ProteinMPNN to design peptide-based inhibitors that target protein pockets closely associated with various diseases. The efficacy of these inhibitors is verified through both in silico and real-world experiments. Second, I develop highly sensitive LC-MS/MS-based analytical methods to quantitatively detect trace-level analytes in complex biological matrices such as cultured meat, and perform thorough validation of these methods. My goal is to contribute to the development of rapid and accurate disease treatments by integrating computer-aided drug design with precision protein analysis technologies.

• Publication

(1) Wonseok Lee*, Ahrum Son*, Jaeho Ji, Eunjeong Han, Ja-Young Cho, Ju-Won Kim, Young-Ok Kim, Hee Jeong Kong#, Hyunsoo Kim#. Elucidating Interactome Dynamics of the A2A Adenosine Receptor. Journal of Proteome Research (ISSN: 1535-3893) Accepted  (IF=3.8, Rank=17.6%) 

• Contact: hej01099139218@gmail.com