• Period: Mar 2026 ~ Present

• Education

Mar 2024 ~ Present B.S., Chemical Engineering and Applied Chemistry, Chungnam National University 

• Project

(1) AI-Driven Design of an AXL-Targeting Peptide Inhibitor

• Summary

My project aims to explore the AI-driven design of peptide-based inhibitors targeting AXL-related protein–protein interactions that contribute to abnormal signaling activation in cancer cells. AXL is a TAM family receptor tyrosine kinase involved in physiological processes such as immune homeostasis. However, dysregulated AXL signaling has been associated with cancer progression, metastasis, cancer cell survival, and therapeutic resistance. Based on this background, this project focuses on the design of peptide candidates that may interfere with these interactions, guided by AI-based protein design tools. These candidates will then be evaluated for their ability to disrupt AXL-mediated interactions, with the goal of investigating the underlying disease mechanisms through targeted inhibition and assessing their therapeutic potential.

• Contact: tlfaleh12@gmail.com