• Period: 2022.09 ~ 2025.02

• Employment:

2021.09 ~ 2022.08 연구원, (주) 지엘팜텍 분석연구팀

• Education:

2016.03 ~ 2022.02 B.S., Pharmaceutical Engineering, Dankook University

• Project:

(1)  Development of an LC-MS-Based Method for Analyzing Therapeutics for Rheumatoid Arthritis

(2)  Establishment of a Hybrid Nano, Capillary, and UPLC-MS System for Targeted Peptide Analysis

(3)  Validation of Laboratory-Developed Tests Targeting

• Summary:

My primary involvement encompasses several key projects: "LC-MS Platform," "Validation of Laboratory-Developed Tests Targeting," and "LC-MS-Based Analysis of Arthritis Therapeutics."

In the "LC-MS Platform" project, our primary focus lies in fine-tuning the analytical conditions of the LC-MS/MS system that has been established within the laboratory.

Within the "Validation of Laboratory-Developed Tests Targeting" initiative, we are actively engaged in method validation for analyzing target proteins associated with various diseases using laboratory-developed tests.

The "LC-MS-Based Analysis of Arthritis Therapeutics" endeavor is centered around creating LC-MS methodologies for scrutinizing the efficacy of the arthritis therapeutic "Synovian," and subsequently conducting thorough efficacy assessments within joint fluid samples. Additionally, there are forthcoming plans to devise an analytical protocol for detecting the specific fungus responsible for Aspergillosis within bronchoalveolar lavage fluid, utilizing LC-MS techniques. Furthermore, leveraging machine learning, we intend to analyze the protein expression levels in bronchoalveolar lavage fluid samples from Aspergillosis patients.

• Publication

(7) Ahrum Son*, Jongham Park, Woojin Kim, Yoonki Yoon, Sangwoon Lee, Jaeho Ji, Hyunsoo Kim#. Recent Advances in Omics, Computational Models, and Advanced Screening Methods for Drug Safety and Efficacy. Toxins (EISSN: 2072-6651), 12 (11), 822 (11/14/2024) (IF=3.9, Rank=21.7%) 

(6) Ahrum Son*, Jongham Park, Woojin Kim, Yoonki Yoon, Sangwoon Lee, Yongho Park, Hyunsoo Kim#. Revolutionizing Molecular Design for Innovative Therapeutic Applications through Artificial Intelligence. Molecules (EISSN: 1420-3049), 29(19), 4626 (09/29/2024) (IF=4.2, Rank=28.1%) 

(5) Ahrum Son*, Woojin Kim, Jongham Park, Yongho Park, Wonseok Lee, Sangwoon Lee, Hyunsoo Kim#. Mass Spectrometry Advancements and Applications for Biomarker Discovery, Diagnostic Innovations, and Personalized Medicine. International Journal of Molecular Sciences (ISSN: 1661-6596), 25(18), 9880 (09/12/2024) (IF=4.9, Rank=21.1%) 

(4) Ahrum Son*, Woojin Kim, Jongham Park, Wonseok Lee, Yerim Lee, Seongyun Choi, Hyunsoo Kim#. Utilizing Molecular Dynamics Simulations, Machine Learning, Cryo-EM, and NMR Spectroscopy to Predict and Validate Protein Dynamics. International Journal of Molecular Sciences (ISSN: 1661-6596), 25(17), 9725 (09/08/2024) (IF=4.9, Rank=21.1%) 

(3) Ahrum Son*, Jongham Park, Woojin Kim, Wonseok Lee, Yoonki Yoon, Jaeho Ji, Hyunsoo Kim#. Integrating Computational Design and Experimental Approaches for Next-Generation Biologics. Biomolecules (EISSN: 2218-273X), 14(9), 1073 (08/27/2024) (IF=4.8, Rank=21.4%)  

(2) Ahrum Son*, Woojin Kim, Wonseok Lee, Jongham Park, Hyunsoo Kim#. Applicability of Selected Reaction Monitoring for Precise Screening Tests. Expert Review of Proteomics (ISSN: 1478-9450), 21, 237-246 (05/08/2024) (IF=3.4, Rank=36.4%)  

(1) Si-Cho Kim*, Da-Won Kim*, Eun Ju Cho*, Jin-Young Lee, Jiwon Kim, Chaesun Kwon, Jeongsil Kim-Ha, Suk Kyun Hong, YoungRok Choi, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Won Kim, Woojin Kim, Hyunsoo Kim, Yoon Jun Kim, Jung-Hwan Yoon, Su Jong Yu#, and Young-Joon Kim#. A circulating cell-free DNA methylation signature for the detection of hepatocellular carcinoma. Molecular Cancer (IF=37.3, Rank=1.4%) (EISSN: 1476-4598) (2023/10/06)

[ Patent ]

(2) 김현수, 김영모, 박종일, 김우진, 손아름. LC-MS/MS 기반의 히알루론산, BDDE, BDDE 가교된 히알루론산 정량법. 대한민국, 10-2766244 (2025/02/06) 

(1) 김현수, 김우진, 손아름. 안정동위원소가 표지된 내부 표준 펩타이드를 이용한 질량분석 기반의 표적 펩타이드의 정량 방법. 대한민국, 10-2691545  (2024/07/30)