Paper

Ahrum Son*, Hyunsoo Kim, Jolene K. Diedrich, Casimir Bamberger, Heather M. Wilkins, Jeffrey M. Burns, Jill K. Morris, Robert A. Rissman, Russell H. Swerdlow, John R. Yates III#. Structural Signature of Plasma Proteins Classifies the Status of Alzheimer’s Disease. Nature Aging (EISSN: 2662-8465) In Revision  (IF=17.0, Rank=1.4%)

Wonseok Lee*, Ahrum Son*, Woojin Kim, Jongham Park, Ja-Young Cho, Ju-Won Kim, Young-Ok Kim, Hee Jeong Kong#, Hyunsoo Kim#. Elucidating Interactome Dynamics of the A2A Adenosine Receptor. Journal of Proteome Research (ISSN: 1535-3893) In Revision  (IF=3.8, Rank=17.6%)

Yu-Min Choi*, Dong Hyun Kim*, Eun Ju Cho*, Ziyun Kim, Junghwa Jang, Hyunsoo Kim, Su Jong Yu#, Bum-Joon Kim#. The sV184A variant in HBsAg specific to HBV subgenotype C2 leads to enhanced viral replication and apoptotic cell death induced by PERK-eIF2α-CHOP-mediated ER stress. Journal of Medical Virology (ISSN: 0146-9071) (02/20/2025) (IF=6.8, Rank=9.8%)

Hee Wook Yang*, Ji-Young Song, Ji-Joon Song, Young Won Kim, Nathan C Rockwell, Woojin Kim, Hyunsoo Kim, J Clark Lagarias, Youn-Il Park#. Dual-Cys Bacteriophytochromes: Intermediates in Cyanobacterial Phytochrome Evolution? FEBS Journal (ISSN: 1742-464X) (01/13/2025) (IF=5.5, Rank=18.5%)

Ahrum Son*, Jongham Park, Woojin Kim, Yoonki Yoon, Sangwoon Lee, Jaeho Ji, Hyunsoo Kim#. Recent Advances in Omics, Computational Models, and Advanced Screening Methods for Drug Safety and Efficacy. Toxins (EISSN: 2072-6651), 12 (11), 822 (11/14/2024) (IF=3.9, Rank=21.7%)

Ahrum Son*, Hyunsoo Kim, Jolene K. Diedrich, Casimir Bamberger, Daniel B. McClatchy, Stuart A. Lipton, John R. Yates III#. Using In Vivo Intact Structure for System-wide Quantitative Analysis of Changes in Proteins. Nature Communications (EISSN: 2041-1723), 15, 9310 (10/29/2024) (IF=14.7, Rank=6.0%) (한빛사)

Ahrum Son*, Jongham Park, Woojin Kim, Yoonki Yoon, Sangwoon Lee, Yongho Park, Hyunsoo Kim#. Revolutionizing Molecular Design for Innovative Therapeutic Applications through Artificial Intelligence. Molecules (EISSN: 1420-3049), 29(19), 4626 (09/29/2024) (IF=4.2, Rank=28.1%)

Ahrum Son*, Woojin Kim, Jongham Park, Yongho Park, Wonseok Lee, Sangwoon Lee, Hyunsoo Kim#. Mass Spectrometry Advancements and Applications for Biomarker Discovery, Diagnostic Innovations, and Personalized Medicine. International Journal of Molecular Sciences (ISSN: 1661-6596), 25(18), 9880 (09/12/2024) (IF=4.9, Rank=21.1%)

Ahrum Son*, Woojin Kim, Jongham Park, Wonseok Lee, Yerim Lee, Seongyun Choi, Hyunsoo Kim#. Utilizing Molecular Dynamics Simulations, Machine Learning, Cryo-EM, and NMR Spectroscopy to Predict and Validate Protein Dynamics. International Journal of Molecular Sciences (ISSN: 1661-6596), 25(17), 9725 (09/08/2024) (IF=4.9, Rank=21.1%)

Ahrum Son*, Jongham Park, Woojin Kim, Wonseok Lee, Yoonki Yoon, Jaeho Ji, Hyunsoo Kim#. Integrating Computational Design and Experimental Approaches for Next-Generation Biologics. Biomolecules (EISSN: 2218-273X), 14(9), 1073 (08/27/2024) (IF=4.8, Rank=21.4%) 

Ahrum Son*, Woojin Kim, Wonseok Lee, Jongham Park, Hyunsoo Kim#. Applicability of Selected Reaction Monitoring for Precise Screening Tests. Expert Review of Proteomics (ISSN: 1478-9450), 21, 237-246 (05/08/2024) (IF=3.4, Rank=36.4%) 

Jongham Park*, Ahrum Son*, Hyunsoo Kim#. A protein–protein interaction analysis tool for targeted cross-linking mass spectrometry. Scientific Reports (ISSN: 2045-2322), 13 (1), 22103 (12/13/2023) (IF=3.8, Rank=18.7%) 

Si-Cho Kim*, Da-Won Kim*, Eun Ju Cho*, Jin-Young Lee, Jiwon Kim, Chaesun Kwon, Jeongsil Kim-Ha, Suk Kyun Hong, YoungRok Choi, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Won Kim, Woojin Kim, Hyunsoo Kim, Yoon Jun Kim, Jung-Hwan Yoon, Su Jong Yu#, Young-Joon Kim#. A circulating cell-free DNA methylation signature for the detection of hepatocellular carcinoma. Molecular Cancer (EISSN: 1476-4598), 22 (1), 164 (10/06/2023) (IF=27.7, Rank=1.4%)

Misol Do*, Hyunsoo Kim*, Injoon Yeo, Jihyeon Lee, In Ae Park, Han Suk Ryu, Youngsoo Kim#. Clinical application of multiple reaction monitoring-mass spectrometry to human epidermal growth factor receptor 2 measurements as a potential diagnostic tool for breast cancer therapy. Clinical Chemistry (ISSN: 0009-9147). 66 (10), 1339-1348 (10/01/2020) (IF=7.3, Rank=3.4%) (한빛사)

Yoseop Kim*, Injoon Yeo*, Hyunsoo Kim, Minsoo Son, Youngsoo Kim#. Preparation of Tissue Samples for Large-scale Quantitative Mass Spectrometric Analysis. Biotechnology and Bioprocess Engineering (ISSN: 1226-8372). 25 (4), 551-561 (07/22/2020) (IF=2.2, Rank=59.6%) 

JaeNyeon Kim*, Injoon Yeo*, Hyunsoo Kim*, Areum Sohn, Yosub Kim, Youngsoo Kim#. Web portal for analytical validation of MRM-MS assay abided with integrative multinational guidelines. Scientific Reports (ISSN: 2045-2322). 10 (1), 1-9 (07/02/2020) (IF=4.0, Rank=23.9%) 

Injoon Yeo*, Gi-Ae Kim*, Hyunsoo Kim*, Ji Hyeon Lee, Areum Sohn, Geum-Youn Gwak, Jeong-Hoon Lee, Young-Suk Lim#, Youngsoo Kim#. Proteome Multimarker Panel with Multiple Reaction Monitoring-Mass Spectrometry for Early Detection of Hepatocellular Carcinoma. Hepatology Communications (ISSN: 2471-254X). 4 (5), 753-768 (03/13/2020)

Hyunsoo Kim*, Yoseop Kim*, Buhm Han, Jin-Young Jang, Youngsoo Kim#. Clinically Applicable Deep Learning Algorithm Using Quantitative Proteomics Data. Journal of Proteome Research (ISSN: 1535-3893). 18 (8), 3195-3202 (07/17/2019) (IF=4.1, Rank=15.6%)

Jihyeon Lee*, Hyunsoo Kim*, Areum Sohn, Injoon Yeo, Youngsoo Kim#. Cost-Effective Automated Preparation of Serum Samples for Reproducible Quantitative Clinical Proteomics. Journal of Proteome Research (ISSN: 1535-3893). 18 (5), 2337-2345 (04/15/2019) (IF=4.1, Rank=15.6%)

Minsoo Son*, Hyunsoo Kim*, Injoon Yeo, Yosub Kim, Areum Sohn, Youngsoo Kim#. Method validation by CPTAC guidelines for multi-protein marker assays using multiple reaction monitoring-mass spectrometry. Biotechnology and Bioprocess Engineering (ISSN: 1226-8372). 24 (2), 343-358 (03/01/2019) (IF=2.2, Rank=59.6%)

Jong su Jun*, Jungsoo Gim, Yongkang Kim, Hyunsoo Kim, Su Jong Yu, Injun Yeo, Jiyoung Park, Jeong-Ju Yoo, Young Youn Cho, Dong Hyeon Lee, Eun Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Seungyeoun Lee, Jung-Hwan Yoon, Youngsoo Kim, Taesung Park#. Analysis of significant protein abundance from multiple reaction-monitoring data. BMC Systems Biology (ISSN: 1752-0509). 12 (9), 123 (12/31/2018) (IF=2.0, Rank=37.3%)

Hyunsoo Kim*, Areum Sohn*, Injun Yeo, Su Jong Yu, Jung-Hwan Yoon, Youngsoo Kim#. Clinical Assay for AFP-L3 by Using Multiple Reaction Monitoring-Mass Spectrometry for Diagnosing Hepatocellular Carcinoma. Clinical Chemistry (ISSN: 0009-9147). 64 (8), 1230-1238 (08/01/2018) (IF=6.9, Rank=3.4%) (한빛사)

Areum Sohn*, Hyunsoo Kim*, Injun Yeo, Yoseop Kim, Minsoo Son, Su Jong Yu, Jung-Hwan Yoon, Youngsoo Kim#. Fully validated SRM-MS-based method for absolute quantification of PIVKA-II in human serum: Clinical applications for patients with HCC. Journal of Pharmaceutical and Biomedical Analysis (ISSN: 0731-7085). 156, 142-146 (07/15/2018) (IF=3.0, Rank=28.6%)

Misol Do*, Dohyun Han*, Joseph Injae Wang, Hyunsoo Kim, Wooil Kwon, SungHyo Park, Youngmin Han, Jin-Young Jang#, Youngsoo Kim#. Quantitative Proteomic Analysis of Pancreatic Cyst Fluid Proteins Associated with Malignancy in Intraductal Papillary Mucinous Neoplasms. Clinical proteomics (ISSN: 1542-6416). 15 (1), 17 (04/18/2018) (IF=2.9, Rank=35.4%)

Jiyoung Park*, Yonghwan Choi*, Junghyun Namkung, Sung Gon Yi, Hyunsoo Kim, Jiyoung Yu, Yongkang Kim, Min-Seok Kwon, Wooil Kwon, Do-Youn Oh, Sun-Whe Kim, Seung-Yong Jeong, Wonshik Han, Kyu Eun Lee, Jin Seok Heo, Joon Oh Park, Joo Kyung Park, Song Cheol Kim, Chang Moo Kang, Woo Jin Lee, Seungyeoun Lee, Sangjo Han, Taesung Park, Jin-Young Jang#, Youngsoo Kim#. Diagnostic performance enhancement of pancreatic cancer using proteomic multimarker panel. Oncotarget (ISSN: 1949-2553). 8 (54), 93117-93130 (01/12/2018)

Hyunsoo Kim*, Joonho Park*, Joseph I. Wang, Youngsoo Kim#. Recent advances in proteomic profiling of pancreatic ductal adenocarcinoma (PDAC) and the road ahead. Expert Review of Proteomics (ISSN: 1478-9450). 14 (11), 963-971 (11/02/2017) (IF=3.5, Rank=30.8%)

Jongmin Woo*, Dohyun Han*, Joseph Wang, Joonho Park, Hyunsoo Kim, Youngsoo Kim#. Quantitative proteomics reveals temporal proteomic changes in signaling pathways during BV2 microglial cell activation. Journal of Proteome Research (ISSN: 1535-3893). 16 (9), 3419-3432 (09/01/2017) (IF=4.0, Rank=17.9%)

Hyunsoo Kim*, JiYoung Park*, Yongkang Kim*, A-Reum Sohn, Injun Yeo, Su Jong Yu, Jung-Hwan Yoon, Taesung Park#, Youngsoo Kim#. Serum fibronectin distinguishes the early stages of hepatocellular carcinoma. Scientific Reports (ISSN: 2045-2322). 7 (1), 9449 (08/25/2017) (IF=4.1, Rank=18.8%)

Hyunsoo Kim*, Su Jong Yu*, Injun Yeo, Young Youn Cho, Dong Hyeon Lee, Yuri Cho, Eun Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Sungyoung Lee, Jongsoo Jun, Taesung Park, Jung-Hwan Yoon#, Youngsoo Kim#. Prediction of Response to Sorafenib in Hepatocellular Carcinoma: A Marker Panel by Multiple Reaction Monitoring-Mass Spectrometry. Molecular & Cellular Proteomics (ISSN: 1535-9476). 16 (7), 1312-1323 (07/01/2017) (IF=5.2, Rank=11.5%)

Areum Sohn*, Hyunsoo Kim*, Su Jong Yu, Jung-Hwan Yoon, Youngsoo Kim#. A quantitative analytical method for PIVKA-II using multiple reaction monitoring-mass spectrometry for early diagnosis of hepatocellular carcinoma. Analytical and Bioanalytical Chemistry (ISSN: 1618-264). 409 (11), 2829-2838 (04/01/2017) (IF=3.3, Rank=19.8%)

Su Jong Yu*, Hyunsoo Kim*, Hophil Min, Areum Sohn, Young Youn Cho, Jeong-Ju Yoo, Dong Hyeon Lee, Eun Ju Cho, Jeong-Hoon Lee, Jungsoo Gim, Taesung Park, Yoon Jun Kim, Chung Yong Kim, Jung-Hwan Yoon, Youngsoo Kim#. Targeted proteomics predict a sustained complete-response after transarterial chemoembolization and clinical outcomes in patients with hepatocellular carcinoma: a prospective cohort study. Journal of Proteome Research (ISSN: 1535-3893). 16 (3), 1239-1248 (03/03/2017) (IF=4.0, Rank=17.7%)

Joo Young Shin*, Areum Sohn, Hyunsoo Kim, Youngsoo Kim, Hyeong Gon Yu#. Carboxymethyl-Lysine-Modified Plasma Proteins in Age-related Macular Degeneration. Biotechnology and Bioprocess Engineering (ISSN: 1226-8372). 22 (1), 52-59 (02/01/2017) (IF=1.2, Rank=85.1%)

Yongkang Kim*, Min-Seok Kwon, Yonghwan Choi, Sung Gon Yi, Junghyun Namkung, Sangjo Han, Wooil Kwon, Hyunsoo Kim, Sun Whe Kim, Jin-Young Jang, Youngsoo Kim, Seungyeoun Lee, Taesung Park#. Comparative studies for developing protein based cancer prediction model to maximize the ROC-AUC with various variable selection methods. International Journal of Data Mining and Bioinformatics (ISSN: 1748-5673). 16 (1), 64-76 (07/01/2016) (IF=0.6, Rank=89.5%)

Yikwon Kim*, MeeJoo Kang*, Dohyun Han, Hyunsoo Kim, KyoungBun Lee, Sun-Whe Kim, Yongkang Kim, Taesung Park, Jin-Young Jang#, Youngsoo Kim#. Biomarker Development for Intraductal Papillary Mucinous Neoplasms Using Multiple Reaction Monitoring Mass Spectrometry. Journal of Proteome Research (ISSN: 1535-3893). 15 (1), 100-113 (01/04/2016) (IF=4.3, Rank=17.9%)

Hyunsoo Kim*, Kyunggon Kim*, Jonghwa Jin, Jiyoung Park, Su Jong Yu, Jung-Hwan Yoon#, Youngsoo Kim#. Measurement of Glycosylated Alpha-Fetoprotein Improves Diagnostic Power over the Native Form in Hepatocellular Carcinoma. PLoS ONE (ISSN: 1932-6203). 9 (10), e110366 (10/13/2014) (IF=3.2, Rank=15.8%)

Jiyoung Yu*, Kyunggon Kim*, MeeJoo Kang, Hyunsoo Kim, Sun Whe Kim, Jin-Young Jang#, Youngsoo Kim#. Development of Candidate Biomarkers for Pancreatic Ductal Adenocarcinoma Using Multiple Reaction Monitoring. Biotechnology and Bioprocess Engineering (ISSN: 1226-8372). 18 (5), 1038-1047 (09/01/2013) (IF=1.2, Rank=75.9%)

Hyunsoo Kim*, Kyunggon Kim*, Su Jong Yu, Eun Sun Jang, Jiyoung Yu, Geunhee Cho, Jung-Hwan Yoon#, Youngsoo Kim#. Development of Biomarkers for Screening Hepatocellular Carcinoma Using Global Data Mining and Multiple Reaction Monitoring. PLoS ONE (ISSN: 1932-6203). 8 (5), e63468 (05/22/2013) (IF=3.5, Rank=14.5%)

Dohyun Han*, Sungyoon Moon, Hyunsoo Kim, Sung-E Choi, Soo-Jin Lee, Kyong Soo Park, Heesook Jun, Yup Kang, Youngsoo Kim#. Detection of Differential Proteomes Associated with the Development of Type 2 Diabetes in the Zucker Rat Model Using the iTRAQ Technique. Journal of Proteome Research (ISSN: 1535-3893). 10 (2), 564-577 (02/04/2011) (IF=5.1, Rank=13.9%)

Kyunggon Kim*, Jiyoung Yu, Hophil Min, Hyunsoo Kim, Byungwook Kim, Hyeong Gon Yu, Youngsoo Kim#. Online monitoring of immunoaffinity-based depletion of high-abundance blood proteins by UV spectrophotometry using enhanced green fluorescence protein and FITC-labeled human serum albumin. Proteome Science (ISSN: 1477-5956). 8 (1), 62 (12/01/2010) (IF=2.5, Rank=49.3%)