이예림 (Yerim Lee)
이예림 (Yerim Lee)
Period: 2023.09. ~ 2024.10.
Employment: 2022.08 ~ 2023.08 주임연구원, (주) 프로메디젠 뉴타겟팀
Education:
2020.03 ~ 2022.02 B.S., Chemical & Biological Engineering, Hanbat National University
2017.03 ~ 2020.02 B.S., Pharmaceutics & Biotechnology, Konyang University
Project:
(1) Identification of Diagnostic Markers for Therapeutic Intervention Through Analysis of COVID-19 Blood Samples
(2) Computational Modeling of Drug-Protein Interactions for Predictive Drug Design
Summary:
At present, I am actively involved in two major research initiatives. The first concentrates on the identification of diagnostic markers for targeted disease treatment and early detection, leveraging single-cell proteomic technologies in the context of COVID-19 blood samples. The second project is centered on the computational investigation of drug-protein interactions.
I am deeply engaged in cutting-edge research aimed at predicting protein-drug interaction sites and decoding structural shifts crucial for rational drug design. My research methodology seamlessly integrates advanced data analytics and machine learning algorithms, with a specific focus on Liquid Chromatography-Mass Spectrometry (LC-MS) techniques.
The core objective of these research undertakings is the engineering of computational algorithms that capitalize on the AlphaFold2-multimer framework for the simultaneous prediction of three-dimensional protein structures and drug binding sites. This initiative is anticipated to enable a comprehensive characterization of complex drug-protein interactions. Ultimately, my goal is to precisely define drug targets, enhancing therapeutic efficacy, mitigating off-target effects, and potentially unveiling new frontiers for drug discovery and therapeutic intervention.